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riboflavin + magnesium
- Development stage
- Unknown
- Lead developer
- Brainwave
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
riboflavin + magnesium is a nutraceutical combination marketed by Brainwave Healthcare for the prophylaxis of migraine. Riboflavin (Vitamin B2) acts as a precursor to flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), which are essential cofactors for the mitochondrial electron transport chain; its supplementation is intended to improve mitochondrial energy production in the brain, addressing metabolic deficits often observed in migraine patients. Magnesium serves as a physiological antagonist of the NMDA receptor and a regulator of various ion channels, helping to maintain ion homeostasis and reduce neuronal hyperexcitability. Together, these components aim to address metabolic and physiological triggers of migraine attacks, providing a non-pharmacological option for reducing headache frequency and severity.
- Other names
- Vitamin B2 + MagnesiumRiboflavin (vitamin B2) + Magnesium combination
02
Targets
NMDAR (Glutamate receptor ionotropic, NMDA)
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