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Rifamycin SV + placebo refers to a clinical trial design where rifamycin SV is compared to placebo. Rifamycin SV is an antibacterial drug that inhibits bacterial DNA-dependent RNA synthesis by binding to prokaryotic RNA polymerase. It is primarily used for the treatment of travelers' diarrhea caused by noninvasive strains of E. coli. The drug is formulated as a delayed-release tablet with a pH-resistant polymer film that breaks down above pH 7, allowing targeted delivery to the intestine.
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