rimantadine

Rimantadine is a synthetic antiviral small molecule used for the prevention and treatment of infections caused by influenza A virus. It acts primarily by inhibiting an early step in the viral replication cycle, likely interfering with the uncoating process of the virus. This effect is mediated through interaction with the M2 protein (matrix protein 2) of influenza A, which is essential for viral replication. Rimantadine has no significant activity against influenza B viruses and does not interfere with immune responses to inactivated influenza vaccines. It is administered orally as tablets or syrup, but its use has declined due to widespread resistance among circulating strains of influenza A[1][2][4][5].

Brand names

Flumadine

Other names

rimantadine hydrochlorideRemantadineRiamantadineMeradane