Drug intelligence / Profile preview

Rinsulin NPH

Development stage
Unknown
Lead developer
Geropharm
Modality
Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

Rinsulin NPH is an intermediate-acting human insulin biosimilar developed by Geropharm using recombinant DNA technology. It is an isophane insulin suspension that acts as an agonist at the insulin receptor (INSR), facilitating glucose uptake in muscle and adipose tissue while inhibiting hepatic glucose production. The drug has an onset of action of approximately 1.5 hours, a peak effect between 4 and 12 hours, and a duration of action up to 24 hours. It is indicated for the management of Type 1 diabetes mellitus, Type 2 diabetes mellitus, and gestational diabetes. Geropharm utilizes full-cycle production technology to manufacture this biologic, which is positioned as a biosimilar to Humulin NPH.

Brand names
Rinsulin NPH
Other names
isophane insulinhuman insulin isophaneNPH insulin
02

Targets

INSR (Insulin receptor)

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