Drug intelligence / Profile preview

RIST472

Development stage
Unknown
Lead developer
Aristea Therapeutics
Modality
Small Molecules
Administration
Oral
01

Overview

RIST472 is a mid-stage oral small molecule developed by Arena Pharmaceuticals and Aristea Therapeutics. It targets the Chemoattractant Receptor-homologous molecule expressed on T-Helper type 2 cells (CRTh2), also known as Prostaglandin D2 receptor 2 (DP2), and was intended for the treatment of immunologic conditions. The drug was later discontinued by Pfizer following its acquisition of Arena Pharmaceuticals.

02

Targets

CXCR2 (C-X-C Motif Chemokine Receptor 2)

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