ritodrine

Ritodrine is a small molecule that functions as a selective beta-2 adrenergic receptor agonist. Its primary therapeutic application is as a tocolytic agent, used to manage and suppress premature uterine contractions in preterm labor. The drug achieves its effect by stimulating beta-2 receptors located on uterine smooth muscle cells, which subsequently increases intracellular cyclic AMP (cAMP) levels and decreases intracellular calcium concentrations. This biochemical cascade leads to the relaxation of the uterine muscles, thereby inhibiting contractions and delaying labor. Ritodrine was first approved for medical use in the United States in 1984, but has since been withdrawn from the U.S. market. It can be administered via intravenous, oral, or intramuscular routes.

Brand names

YutoparPre-ParUtoparRitopar URRitrodTocoparUtodinRitolanUnisoxRitoberUtbestRitodineMiolene

Other names

ritodrine hydrochloride