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rituximab + gemcitabine + oxaliplatin + dexamethasone

Development stage
Unknown
Lead developer
IDEC
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration
Intravenous, Oral
01

Overview

A combination chemotherapy regimen consisting of rituximab, gemcitabine, oxaliplatin, and dexamethasone used primarily for the treatment of relapsed or refractory non-Hodgkin lymphoma, particularly diffuse large B-cell lymphoma (DLBCL) and peripheral T-cell lymphoma (PTCL). This regimen has shown efficacy in patients who are not candidates for high-dose therapy and autologous stem cell transplantation.

Other names
R-GemDOxRGDOx
02

Targets

GR (Glucocorticoid receptor)CD20 (B-lymphocyte antigen CD20)DNA

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