Drug intelligence / Profile preview

RJ4377

Development stage
Preclinical
Lead developer
Nanjing Ruijie Pharmaceutical Technology
Modality
Small Molecules
01

Overview

RJ4377 is a small molecule inhibitor of spleen tyrosine kinase (SYK) currently in the discovery stage of development by Nanjing Ruijie Pharma. SYK is a cytoplasmic protein tyrosine kinase that mediates signal transduction downstream of various receptors, including the B-cell receptor and Fc receptors, making it a target for autoimmune diseases and hematological malignancies. While the specific indications for RJ4377 remain undisclosed, it belongs to a portfolio of SYK inhibitors being explored by the developer for immune-mediated conditions.

02

Targets

SYK (Spleen Tyrosine Kinase)

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