Drug intelligence / Profile preview

RKD002

Development stage
Preclinical
Lead developer
RevolKa
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

RKD002 is a preclinical-stage mRNA-based therapeutic being developed by RevolKa for the treatment of an undisclosed rare disease. The drug utilizes RevolKa's proprietary protein engineering platform, which combines directed evolution with artificial intelligence (AI) to design optimized proteins. RKD002 specifically consists of a gain-of-function (GOF)-enhanced mRNA designed to express a novel, AI-optimized enzyme. This approach aims to address rare genetic disorders by providing functional enzymatic activity that is superior to the wild-type protein. As of 2024, the specific molecular target and the exact rare disease indication remain undisclosed by the sponsor.

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