Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
RLLRRLLR-Ahx-RWQWRWQWR
- Development stage
- Preclinical
- Lead developer
- Universidad Nacional de Colombia
- Modality
- Peptides
01
Overview
RLLRRLLR-Ahx-RWQWRWQWR is a synthetic hybrid anticancer peptide (ACP) designed for the treatment of cervical cancer. It is composed of a sequence derived from Buforin IIb (RLLRRLLR) and a palindromic sequence derived from bovine lactoferricin (RWQWRWQWR), connected by a 6-aminohexanoic acid (Ahx) spacer. The peptide exhibits rapid, concentration-dependent cytotoxic activity against cervical cancer cell lines such as HeLa and Ca Ski. Its mechanism of action involves initial electrostatic interaction with negatively charged cell surface components, followed by membrane disruption or internalization that leads to cell death, characterized by morphological changes consistent with apoptosis. It was developed through a collaboration between the Universidad Nacional de Colombia and Pontificia Universidad Javeriana.
- Other names
- Hybrid peptide 4Buforin IIb-LfcinB hybrid peptide
Beyond the preview
Go deeper on RLLRRLLR-Ahx-RWQWRWQWR.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on RLLRRLLR-Ahx-RWQWRWQWR.