Drug intelligence / Profile preview

rM28

Development stage: Phase 2
Modality: Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics

Overview

rM28 is a recombinant bispecific single-chain antibody designed to enhance cytotoxic T-cell recognition of melanoma cells by targeting both CD28 and MAPK. This mechanism may improve the immune response against melanoma.

Targets

MAPK3 (Mitogen-activated protein kinase 1)CD28 (Cluster of Differentiation 28)

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