Drug intelligence / Profile preview

RMD-002

Development stage
Preclinical
Lead developer
Remedium Bio
Modality
Gene Therapies, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Subcutaneous
01

Overview

RMD-002 (also referred to as RMD-1202) is a preclinical gene therapy candidate being developed by Remedium Bio (Remedium Technologies) for the treatment of obesity and Type 2 Diabetes. The therapy utilizes the company's proprietary Prometheus™ adjustable gene therapy platform, which is designed for delivery via either adeno-associated virus (AAV) or lipid nanoparticle (LNP) vectors. RMD-002 is engineered to enable the continuous subcutaneous production of a GLP-1 receptor agonist following a single injection, aiming to replace the requirement for frequent protein injections. By providing stable, steady-state protein expression and eliminating the concentration spikes associated with traditional dosing, the therapy seeks to improve weight loss efficacy, glycemic control, and insulin response while enhancing safety and tolerability.

02

Targets

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