Drug intelligence / Profile preview

RMP-A03

Development stage
Phase 2
Lead developer
Suzhou Ruiming New Drug Research & Development
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

RMP-A03 is a small molecule chemical drug developed for the treatment of pterygium, an ocular surface disease characterized by abnormal fibrovascular growth on the conjunctiva. The drug is being evaluated as an ocular suspension and has completed Phase 2 clinical trials assessing its safety and efficacy in patients with pterygium. The precise mechanism of action for RMP-A03 remains unknown, and it does not represent a novel mechanism of action. The developer and active organization behind this compound is Suzhou Ruiming New Drug Research & Development Co., Ltd., also referred to as Suzhou Raymon Pharmaceuticals Company, Ltd.[1][2][3]

Other names
nintedanib ophthalmic
02

Targets

FGFR1 (Fibroblast growth factor receptor 1)FGFR2 (Keratinocyte growth factor receptor)FGFR3 (Fibroblast growth factor receptor 3)PDGFRA (Platelet-derived growth factor receptor alpha)PDGFRB (Platelet-derived growth factor receptor beta)VEGFR-1 (Vascular endothelial growth factor receptor 1)VEGFR2 (Vascular endothelial growth factor receptor 2)VEGFR4 (Vascular endothelial growth factor Receptor-3)Tyrosine kinase

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