Drug intelligence / Profile preview

Rohto

Development stage
Unknown
Lead developer
Rohto Pharmaceutical
Modality
Small Molecules
Administration
Topical, Ophthalmic
01

Overview

Rohto is a globally recognized brand of over-the-counter (OTC) ophthalmic solutions developed by Rohto Pharmaceutical. The brand encompasses a wide range of formulations tailored for various ocular conditions, including eye redness, dryness, itchiness, and fatigue. A hallmark of many Rohto products is the signature cooling sensation provided by ingredients like menthol, which target the TRPM8 receptor. The product line includes flagship brands such as V Rohto, Rohto Dry Aid, and Algard. Active ingredients typically include vasoconstrictors like naphazoline or tetrahydrozoline to reduce redness, antihistamines like pheniramine for allergy relief, and various lubricants and vitamins to support ocular health. Rohto also produces the V5 line, which focuses on dietary supplements for vision support.

Brand names
RohtoV RohtoRohto V5Rohto Dry AidAlgardRohto CoolRohto IceV Rohto Premium
Other names
Rohto Eye Drops
02

Targets

ADRA1A (α1A)ADRA2A (α2A)HRH1 (Histamine H1 Receptor)

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