Drug intelligence / Profile preview

rokitamycin

Development stage
Unknown
Lead developer
Taisho Pharmaceutical
Modality
RNA-Targeting Small Molecules → Nucleic Acid-Directed Small Molecules → Small Molecules
Administration
Oral
01

Overview

Rokitamycin is a macrolide antibiotic synthesized from strains of *Streptomyces kitasatoensis*. It is primarily active against Gram-positive bacteria and functions by inhibiting bacterial protein synthesis through specific binding to the 50S subunit of the ribosome, thereby blocking translation in susceptible organisms. This mechanism confers selectivity for prokaryotes due to the absence of 50S ribosomes in eukaryotic cells. Rokitamycin has been used mainly for respiratory tract infections and is considered well-tolerated with a low incidence of adverse reactions[3][4][5][7].

Brand names
Rokitamycin
Other names
RicamycinRokitamicinaRokitamycine
02

Targets

Bacterial 50S ribosomal subunit

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