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ropivacaine + betamethasone dipropionate + betamethasone sodium phosphate
- Development stage
- Unknown
- Lead developer
- Beijing Tiantan Hospital
- Modality
- Small Molecules
- Administration
- Percutaneous
01
Overview
Ropivacaine + Diprospan is a combination analgesic regimen used for pre-incisional local infiltration to manage postoperative pain, particularly following laparoscopic surgery. Ropivacaine is a long-acting aminoamide local anesthetic that inhibits nerve conduction by blocking voltage-gated sodium channels. Diprospan is a corticosteroid formulation containing betamethasone dipropionate and betamethasone sodium phosphate, which provides both immediate and sustained anti-inflammatory effects by activating glucocorticoid receptors. This combination aims to prolong the duration of analgesia and reduce the inflammatory response at the surgical site. It is currently being evaluated in clinical trials led by Beijing Tiantan Hospital.
- Other names
- ropivacaine + diprospanropivacaine plus diprospan
02
Targets
GR (Glucocorticoid receptor)NaV (Voltage-gated sodium channels)
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