Drug intelligence / Profile preview

ropivacaine + radiopaque contrast

Development stage
Unknown
Lead developer
AstraZeneca
Modality
Small Molecules
Administration
Epidural, Perineural, Intraarticular
01

Overview

Ropivacaine + radiopaque contrast is a combination used primarily in interventional pain management and regional anesthesia procedures, particularly for continuous epidural infusion. Ropivacaine is an amide-type local anesthetic that works by blocking sodium channels on nerve fibers, thereby inhibiting the initiation and conduction of nerve impulses to provide regional or local anesthesia and acute pain relief. The addition of a radiopaque contrast agent (commonly iohexol or other iodinated compounds) allows real-time imaging (e.g., under CT or fluoroscopy) to visualize the spread of the anesthetic solution within the epidural space, ensuring accurate placement and distribution. This combination is not a commercial product but rather a procedural mixture prepared for specific clinical indications where both analgesia and imaging guidance are required[1][8]. The primary indication is for procedures requiring both effective pain control and confirmation of drug spread via imaging.

02

Targets

SCN1A (Voltage-gated sodium channel protein type 1 subunit alpha)

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