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Rosa damascena dry extract
- Development stage
- Unknown
- Lead developer
- Galen-N
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral, Topical
01
Overview
Rosa damascena dry extract is a dry botanical extract manufactured from the fresh blossoms of *Rosa damascena* (Damask rose). Produced by Galen-N, the extract is obtained via water-ethanol extraction, vacuum concentration, and spray drying. It is rich in active phytochemicals, including phenolic compounds, flavonoid glycosides (such as quercetin and kaempferol), catechins, tannins, and anthocyanins. The extract is marketed as a bulk pharmaceutical, nutraceutical, and cosmetic ingredient, possessing antioxidant, anti-inflammatory, analgesic, laxative, and potential bronchodilator properties.
- Other names
- Bulgarian rose dry extractRosa damascena extractRosa damascena flower extractrose dry extract
02
Targets
AcetylcholinesteraseSucrase-IsomaltaseAβ (Amyloid-beta peptides and aggregates)BACE1 (Beta-site APP-cleaving enzyme 1)M1 (Muscarinic acetylcholine receptor M1)P. gingivalis (Porphyromonas gingivalis)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)NFKB1 (NF-κB1)
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