Drug intelligence / Profile preview

rosa moschata extract

Development stage
Unknown
Administration
Oral, Topical
01

Overview

Rosa moschata extract is a plant-derived product obtained from the fruit, leaves, or seeds (commonly rosehip) of the Rosa moschata (musk rose) shrub. Traditionally used in folk medicine, contemporary pharmacological studies demonstrate antispasmodic and antidiarrhoeal activity, likely owing to voltage-gated calcium channel blockade, resulting in gut motility inhibition. Additional evidence indicates neuroprotective, anticonvulsant, antioxidant, anticholinesterase, and memory-enhancing effects in experimental models, possibly mediated by modulation of oxidative stress markers, neurotransmitter systems, anti-inflammatory pathways, and GABAA receptor upregulation. Cosmetically, the extract (especially oil) is valued for its high content of essential fatty acids (linoleic, omega 3, 6, and 9), vitamins (A, C, and E), and antioxidants, supporting skin regeneration, wound healing, and anti-aging effects[1][2][3][4][5][6].

Other names
rosa moschata fruit extractrosa moschata leaf extractrosa moschata oilmusk rose extractrosehip extractrosa moschata (J) extractRMLE
02

Targets

CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)

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