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Rose hip seed oil is a lipid-rich extract obtained from the seeds of wild rose bushes, primarily *Rosa canina*, *Rosa rubiginosa*, or *Rosa moschata*. It is characterized by a high content of essential fatty acids, specifically linoleic acid (C18:2 n-6) and alpha-linolenic acid (C18:3 n-3), which are critical for maintaining the integrity of the skin's stratum corneum and barrier function. The oil also contains significant levels of all-trans retinoic acid (tretinoin), tocopherols, and carotenoids, which contribute to its regenerative and antioxidant properties. Its mechanism of action involves the inhibition of pro-inflammatory enzymes such as cyclooxygenase (COX-1 and COX-2) and lipoxygenase, as well as the modulation of cytokine production. Clinically, it is utilized topically to improve the appearance of scars, striae, and photoaging, and is occasionally used as a dietary supplement to support joint health and systemic anti-inflammatory responses.
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