Drug intelligence / Profile preview

rose oil

Development stage
Unknown
Modality
Small Molecules
Administration
Inhalation, Topical, Oral, Per Vaginum
01

Overview

Rose oil, primarily derived from *Rosa damascena* (Damask rose), is an essential oil containing bioactive monoterpenoids such as geraniol, citronellol, and nerol. It is utilized for its analgesic, anti-inflammatory, anxiolytic, and antimicrobial properties. Clinical research has investigated its use in reducing dental anxiety, procedural pain, and menopausal vasomotor symptoms. Mechanistically, it modulates inflammatory cytokines (IL-6, TNF-α, IL-1β), disrupts microbial membranes, and interferes with viral adsorption (e.g., HSV-1). Additionally, components like geraniol have been shown to upregulate albumin expression, suggesting potential benefits for age-related malnutrition.

Other names
Damask rose essential oilRosa damascena oilrose essential oilTurkish rose oil
02

Targets

gD (HSV-2 glycoprotein D)

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