Drug intelligence / Profile preview

roselle

Development stage
Phase 3
Lead developer
Natural Wellness
Administration
Oral
01

Overview

Roselle refers to the plant *Hibiscus sabdariffa*, which is widely utilized in traditional medicine and as a dietary supplement for its antioxidant and antihypertensive properties. In a specific clinical context, **NW Roselle** is a powdered medicinal product developed by Natural Wellness that combines extracts from *Hibiscus sabdariffa* flowers and *Olea europaea* (olive) leaves. This combination is primarily investigated for the treatment of Grade 1 essential hypertension, where it is thought to exert therapeutic effects through angiotensin-converting enzyme (ACE) inhibition, diuretic activity, and vasodilatory mechanisms. Beyond hypertension, roselle extracts have been studied for their potential to reduce insulin resistance in type 2 diabetes and for their in vitro cytotoxic effects against oral squamous cell carcinoma cells, likely mediated by high concentrations of anthocyanins, polyphenols, and flavonoids.

Brand names
NW Roselle
Other names
Hibiscus sabdariffasour teakarkadered sorrel
02

Targets

ACE (Angiotensin Converting Enzyme)

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