Drug intelligence / Profile preview

ROSULA CLK

Development stage
Unknown
Lead developer
Fougera Pharmaceuticals
Modality
Small Molecules
Administration
Topical
01

Overview

ROSULA CLK is a prescription topical kit developed by Bradley Pharmaceuticals (through its Doak Dermatologics subsidiary) for the treatment of acne vulgaris, acne rosacea, and seborrheic dermatitis. The kit consists of two distinct components: ROSULA Clarifying Wash and A-FIL Cream. The wash component contains 10% sodium sulfacetamide, 4% sulfur, and urea, providing antibacterial and keratolytic effects. Sodium sulfacetamide acts as a sulfonamide antibiotic that inhibits bacterial growth by competing with p-aminobenzoic acid (PABA), while sulfur serves as a keratolytic agent to reduce inflammation and promote skin turnover. The A-FIL Cream component is a tinted sunscreen containing 5% meradimate and 5% titanium dioxide (SPF-25) to protect the skin from UV radiation, which can exacerbate rosacea and acne symptoms.

Brand names
ROSULA CLK
Other names
ROSULA Clarifying Wash + A-FIL Cream
02

Targets

DHPS (Dihydropteroate synthase)

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