Drug intelligence / Profile preview

Rotavirus vaccine

Development stage
Approved
Lead developer
GSK
Modality
Live Biotherapeutic Products → Microbiome Therapeutics, Vaccines & Immunotherapeutics
Administration
Oral
01

Overview

Rotavirus vaccine is a live attenuated oral vaccine used to prevent infections caused by rotavirus, the leading cause of severe diarrhea and dehydration in infants and young children. The vaccines work by stimulating an immune response against the virus without causing disease. There are two main brands currently in use globally—Rotarix (monovalent) and RotaTeq (pentavalent)—both administered orally in a series of 2 or 3 doses depending on the product. These vaccines significantly reduce hospitalizations and deaths due to severe gastroenteritis caused by multiple strains of rotavirus. The World Health Organization recommends their inclusion in all national immunization programs[1][2][3][4][5].

Brand names
RotarixRotaTeq
Other names
human rotavirus vaccinelive attenuated rotavirus vaccine
02

Targets

RVA (Rotavirus A)

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