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rotavirus vaccine, live, oral, pentavalent
- Development stage
- Approved
- Lead developer
- Merck
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Oral
01
Overview
**Rotavirus vaccine, live, oral, pentavalent** is a live human-bovine reassortant rotavirus vaccine marketed as **RotaTeq**. It contains five live reassortant rotaviruses based on the attenuated bovine WC3 strain background and expressing human rotavirus surface antigens representing G1, G2, G3, G4, and P1A[8] types. Administered orally as a three-dose infant series, it induces active immunity against rotavirus and is approved to prevent rotavirus gastroenteritis caused by G1, G2, G3, G4, and G9 rotavirus types in infants aged 6 to 32 weeks. ([fda.gov](https://www.fda.gov/media/75718/download))
- Brand names
- RotaTeq
- Other names
- live pentavalent human-bovine reassortant rotavirus vaccinepentavalent human-bovine reassortant rotavirus vaccinepentavalent rotavirus vaccinePRVRV5RV-5RV 5rotavirus vaccine, live, oral
02
Targets
HBGA (Histo-blood group antigen)
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