Drug intelligence / Profile preview

Rowatanal

Development stage
Unknown
Lead developer
Rowa
Modality
Small Molecules
Administration
Topical, Rectal
01

Overview

Rowatanal is a topical cream indicated for the symptomatic relief of pain, itching, and discomfort associated with internal and external hemorrhoids (piles), anal pruritus, and perianal irritation. Developed by Rowa Pharmaceuticals and marketed in the Philippines by New Marketlink Pharmaceutical Corporation, the formulation typically combines astringent and protective agents such as bismuth subgallate and zinc oxide with the soothing properties of menthol. Bismuth subgallate and zinc oxide act as mild antiseptics and astringents that form a protective layer over the affected mucosa, helping to reduce inflammation and protect the area from further irritation. Menthol provides a cooling sensation and relieves itching by activating TRPM8 receptors. The product is applied topically to the affected area or rectally using an applicator nozzle for internal treatment.

Brand names
Rowatanal
Other names
Rowatanal Cream
02

Targets

TRPM8 (Transient receptor potential cation channel subfamily M member 8)

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