Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
RP-7
- Development stage
- Preclinical
- Lead developer
- University of North Texas Health Science Center
- Modality
- Peptides
- Administration
- Intraperitoneal, Intravenous
01
Overview
RP-7 is a first-in-class bioactive peptide designed based on the conserved prenylation motif of the Migration and Invasion Enhancer 1 (MIEN1) protein. Developed by researchers at the University of North Texas Health Science Center, RP-7 targets the MIEN1 signaling pathway to inhibit cancer cell migration, invasion, and epithelial-mesenchymal transition (EMT). It physically binds to MIEN1, forming a MIEN1-peptide complex, and suppresses epidermal growth factor (EGF)-induced nuclear factor kappa B (NF-κB) nuclear translocation. In preclinical models of metastatic breast cancer, RP-7 has demonstrated significant inhibition of tumor growth and is well-tolerated.
- Other names
- D-RP-7D-RP7D-RP 7L-RP-7L-RP7L-RP 7RP-7 peptideRP7 peptideRP 7 peptideRPPCVIL
02
Targets
MIEN1 (Migration and invasion enhancer 1)
Beyond the preview
Go deeper on RP-7.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on RP-7.