Drug intelligence / Profile preview

RQ-2060

Development stage
Preclinical
Lead developer
RNACure Biopharma
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration
Intravenous
01

Overview

RQ-2060 is an mRNA-encoded T-cell engager (TCE) being developed by RNAcure for the treatment of various cancers. As an mRNA-based therapeutic, it is designed to be delivered into the patient's cells, which then translate the mRNA into a bispecific T-cell engager protein. This protein typically binds to a specific tumor-associated antigen on cancer cells and the CD3 receptor on T cells, thereby redirecting the patient's immune system to recognize and eliminate tumor cells. While the specific molecular targets for RQ-2060 have not been publicly disclosed, the program represents a shift from traditional recombinant protein TCEs toward in vivo production via mRNA technology.

02

Targets

CD3 (T-cell surface glycoprotein CD3)

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