Drug intelligence / Profile preview

RQ-2500

Development stage
Preclinical
Lead developer
RNAcure
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

RQ-2500 is a personalized mRNA-based cancer vaccine being developed by RNAcure. The therapeutic approach involves identifying unique mutations, known as neoantigens, within a patient's tumor through genomic sequencing and encoding these specific sequences into an mRNA molecule. Once administered, the vaccine is designed to prompt the patient's immune system to recognize and attack cells expressing these neoantigens, thereby providing a highly specific anti-tumor response. This personalized modality aims to overcome the limitations of broad-spectrum therapies by tailoring the treatment to the individual genetic profile of the patient's cancer, potentially improving efficacy while minimizing systemic toxicity.

02

Targets

Patient-specific tumor neoantigen peptides presented by major histocompatibility complex

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