Drug intelligence / Profile preview

RQ3033

Development stage
Discontinued
Lead developer
Walvax Biotechnology
Modality
Vaccines & Immunotherapeutics, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Administration
Intramuscular
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Overview

RQ3033 is an mRNA-based COVID-19 vaccine developed by Walvax Biotechnology in collaboration with Fudan University and Shanghai RNACure Biopharma. It is specifically designed to target the SARS-CoV-2 Omicron XBB.1.5 variant. The vaccine utilizes mRNA technology to encode the viral spike protein, which, upon administration, is translated by host cells to stimulate the production of neutralizing antibodies and T-cell responses against the virus. In December 2023, RQ3033 was granted emergency use authorization (EUA) by the National Medical Products Administration (NMPA) in China for use as a booster dose to address the prevalence of XBB subvariants.

02

Targets

SARS-CoV-2 spike

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