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RSN0402 is a small molecule investigational drug developed by Shenzhen Resproly Biopharmaceutical for the treatment of idiopathic pulmonary fibrosis (IPF). It is classified as an antifibrotic agent, though its precise mechanism of action remains undefined. The drug is being developed as an inhaled powder formulation, aiming to deliver targeted therapy directly to the lungs and reduce systemic side effects compared to oral antifibrotics. Preclinical studies have shown that RSN0402 was safe, well tolerated, and significantly reduced lung fibrosis and inflammation. As of July 2024, it is in phase 1 clinical trials in Australia for IPF[1][5][8].
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