Drug intelligence / Profile preview

rsRNA-28S antisense oligonucleotide

Development stage
Preclinical
Modality
MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01

Overview

rsRNA-28S antisense oligonucleotide is an experimental **antisense oligonucleotide** reagent designed to inhibit a specific 28S ribosomal RNA-derived small RNA, rsRNA-28S. Based on the cited publication context, it was used as a sequence-specific RNA knockdown tool in prostate cancer models to counter the biologic effects of rsRNA-28S, which was reported to regulate chemoresistance through the PTGIS axis. There is no clear evidence from the provided source that this agent has an established proprietary nonproprietary name, sponsor-backed clinical development program, marketed product identity, or defined pharmaceutical formulation beyond its use as a research oligonucleotide.

Other names
rsRNA-28S antisense oligonucleotidersRNA28S antisense oligonucleotidersRNA 28S antisense oligonucleotideantisense oligonucleotide against rsRNA-28S
02

Targets

28S rRNA (28S ribosomal RNA)

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