Drug intelligence / Profile preview

RSS0343

Development stage
Phase 2
Lead developer
Reistone Biopharma
Modality
Small Molecules
Administration
Oral
01

Overview

RSS0343 is a small molecule inhibitor of dipeptidyl peptidase 1 (DPP-1, also known as cathepsin C), developed for the treatment of immune system and respiratory diseases. Its primary mechanism is inhibition of DPP-1, an enzyme involved in the activation of neutrophil serine proteases that play a role in inflammatory processes. The drug was initially developed by Reistone Biopharma and is now being advanced by Jiangsu Hengrui Pharmaceuticals. It is currently in Phase 2 clinical trials for non-cystic fibrosis bronchiectasis and asthma[1][4][5].

Brand names
RSS0343 TabellaRSS-0343 TabellaRSS 0343 Tabella
Other names
RSS0343RSS-0343RSS 0343
02

Targets

CTSC (DPP1)

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