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RSV F antigen
- Development stage
- Unknown
- Lead developer
- GSK
- Modality
- Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
- Administration
- Intranasal, Subcutaneous
01
Overview
The Respiratory Syncytial Virus (RSV) F antigen, also known as the RSV fusion (F) glycoprotein, is a surface protein of the Respiratory Syncytial Virus. It is a primary target for neutralizing antibodies and exists in both pre-fusion and post-fusion conformations. This protein is a critical component in the development of RSV vaccines, where it is used to elicit a protective immune response against RSV infection. Vaccines containing the RSV F antigen aim to induce robust antibody responses, including neutralizing antibodies, to prevent lower respiratory tract infections caused by RSV, particularly in vulnerable populations such as infants and older adults.
- Other names
- RSV F proteinfusion (F) glycoproteinpre-fusion (pre-F)postfusion RSV F
02
Targets
RSV F (Respiratory syncytial virus fusion protein)
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