Drug intelligence / Profile preview

RSVpreF + BNT162b2

Development stage
Unknown
Lead developer
Pfizer
Modality
Recombinant Proteins and Enzymes, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

RSVpreF + BNT162b2 is a combination of two vaccines: RSVpreF, a bivalent prefusion F protein-based vaccine targeting respiratory syncytial virus (RSV) subgroups A and B, and BNT162b2, an mRNA-based COVID-19 vaccine encoding the spike protein of SARS-CoV-2. The combination is being studied for concomitant or admixed administration to protect older adults against both RSV and COVID-19. Clinical studies in adults aged 65 years or older have shown that the combined or coadministered vaccines are safe, well tolerated, and elicit noninferior immune responses compared to each component given alone. This approach aims to improve vaccination rates by simplifying immunization schedules for multiple respiratory pathogens[1][2][5].

Brand names
AbrysvoComirnaty
Other names
bivalent respiratory syncytial virus prefusion F vaccine + bivalent mRNA COVID-19 vaccinecombined RSV and COVID-19 vaccine
02

Targets

SARS-CoV-2 spikeRSV F (Respiratory syncytial virus fusion protein)

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