Drug intelligence / Profile preview

RT-102

Development stage
Unknown
Lead developer
RANI Therapeutics
Modality
Peptides
Administration
Oral
01

Overview

**RT-102** is Rani Therapeutics' investigational oral formulation of **teriparatide**, the human parathyroid hormone fragment PTH (1-34), delivered using the RaniPill GO robotic capsule. The capsule is designed to release and deliver the peptide in the small intestine, providing systemic exposure without a conventional subcutaneous injection. Teriparatide acts as an anabolic bone therapy through agonism of parathyroid hormone 1 receptor, promoting bone formation with intermittent exposure. RT-102 completed a Phase 1 pharmacokinetic, safety, and tolerability study in healthy adult women and was being developed for osteoporosis. ([ir.ranitherapeutics.com](https://ir.ranitherapeutics.com/news-releases/news-release-details/rani-therapeutics-presentation-oral-delivery-pth-osteoporosis))

Other names
oral teriparatideoral parathyroid hormone 1-34
02

Targets

PTH1R (Parathyroid hormone/Parathyroid hormone-related peptide receptor type 1)

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