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rTAT-PTD-Trp2Δ
- Development stage
- Preclinical
- Modality
- Peptide Conjugates → Peptides
- Administration
- Experimental/in Vitro (commonly Used In Cell Culture Or Preclinical Settings), Intradermal Or Intravenous (potential, Based On Typical Cpp Conjugate Use)
01
Overview
rTAT-PTD-Trp2Δ is an experimental **cell-penetrating peptide (CPP) conjugate** designed to deliver the Trp2Δ peptide sequence into cells. The rTAT component serves as a potent cell-penetrating peptide, increasing membrane permeability to enable intracellular delivery. The drug is typically researched for its utility in facilitating intracellular delivery of biologically active peptide sequences, especially for modulating immune responses or intracellular protein-protein interactions. The precise mechanism of action depends on the cargo peptide (here Trp2Δ), but generally, the rTAT-PTD enables cytosolic transport, potentially for antitumor immunomodulation or related peptide therapeutics. There is no evidence of commercial availability or advanced clinical development for this specific conjugate[6].
- Other names
- rTAT-PTD-Trp2Δ
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