Drug intelligence / Profile preview

rTMS-COG

Development stage
Preclinical
Administration
Transcranial
01

Overview

rTMS-COG refers to a specific protocol or application of repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training, primarily investigated for the treatment of cognitive impairment in conditions such as Alzheimer’s disease. The approach involves delivering repeated magnetic pulses to targeted brain regions using an electromagnetic coil placed on the scalp, which induces electrical currents in underlying neural tissue and modulates neuronal activity. In the context of "COG," this typically means pairing rTMS with cognitive exercises or interventions aimed at enhancing memory, attention, or other cognitive functions[6][8]. This noninvasive therapy is considered safe and has shown promise in improving cognitive scores in clinical trials involving patients with mild-to-moderate Alzheimer’s disease[6][8].

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