Drug intelligence / Profile preview

Ruanmaijian decoction

Development stage
Preclinical
Lead developer
Longhua Hospital Shanghai University of Traditional Chinese Medicine
Administration
Oral
01

Overview

Ruanmaijian decoction (also known as Yishen Huazhuo decoction) is a Traditional Chinese Medicine (TCM) herbal formula developed by Longhua Hospital, affiliated with the Shanghai University of Traditional Chinese Medicine. It is primarily indicated for the treatment of atherosclerosis and carotid atherosclerosis, specifically in patients presenting with the 'kidney-deficiency' syndrome according to TCM diagnostics. The decoction is typically administered as an adjunct to standard Western medical treatments, such as statins, to enhance the stabilization and regression of atherosclerotic plaques. Its therapeutic approach, 'Yishen Huazhuo,' focuses on tonifying the kidney and clearing metabolic 'turbidity' (lipids and inflammation) to improve vascular function and reduce cardiovascular risk.

Other names
RuanmaijianYishen Huazhuo decoctionYishen Huazhuo formulaYishen Huazhuo Ruanmaijian decoction
02

Targets

MAPK3 (Mitogen-activated protein kinase 1)Ephrin type-A receptor 2/ephrin-A1 pathway

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