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RV4104A

Development stage
Phase 4
Lead developer
Pierre Fabre
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

RV4104A is an experimental topical antifungal ointment developed for the treatment of **onychomycosis** (fungal nail infection), particularly infections exclusively due to dermatophytes. It has been studied as the initial part of a **sequential therapy**, followed by ciclopiroxolamine cream and ciclopirox film-forming solution, in clinical trials comparing its efficacy and safety to standard therapies such as amorolfine nail lacquer. The formulation and exact mechanism of action are not publicly disclosed in available literature, but it is presumed to act as an **antifungal agent** applied topically to the nail, aiming to disrupt fungal growth by action on the nail plate and adjacent periungual tissues[2][4][5][6]. The main clinical studies were led by Pierre Fabre Dermo Cosmetique; the therapeutic sequence is unique in targeting dermatophytic onychomycosis without matrix involvement. No specific information is available regarding the molecular identity or broader pharmacological classification of RV4104A beyond its antifungal clinical utility.

Other names
RV4104A ointmentRV-4104A ointmentRV 4104A ointment

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