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RY_SW01
- Development stage
- Unknown
- Lead developer
- Jiangsu Lianhuan Pharmaceutical
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
RY_SW01 is a mesenchymal stem cell (MSC) therapy developed by Jiangsu Renocell Biotech for the treatment of autoimmune and fibrotic diseases. It is currently being evaluated in Phase I/II clinical trials for systemic sclerosis (SSc) and active lupus nephritis. The therapy is designed to modulate the immune system and counteract tissue fibrosis, potentially offering a long-term benefit for patients who have failed conventional therapies like steroids and immunosuppressants. In clinical research, a radiolabeled version, 89Zr-Oxine-RY_SW01, has been utilized to characterize the in vivo distribution and metabolic kinetics of the cells. Preclinical data indicates that RY_SW01 can significantly improve biochemical indicators and reduce tissue damage in animal models of lupus without evidence of rejection.
- Other names
- RY_SW01细胞注射液RY_SW01 Cell Injection
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