Drug intelligence / Profile preview

Rybix

Development stage
Unknown
Lead developer
Shionogi
Modality
Small Molecules
Administration
Oral
01

Overview

**Rybix** is an **orally disintegrating tablet (ODT)** formulation of **tramadol**, a centrally acting synthetic opioid analgesic approved for the management of moderate to moderately severe pain in adults. It provides rapid dissolution and absorption for quicker onset compared to standard tablets, with each 50mg tablet containing tramadol hydrochloride as the active ingredient. Developed and launched by Victory Pharma, it belongs to the opioid class but has a unique dual mechanism as a weak μ-opioid receptor agonist and serotonin/norepinephrine reuptake inhibitor (SNRI), offering about 1/10th the potency of morphine with additional effects on descending pain inhibitory pathways.[1][2][3][6]

Brand names
RybixRybix ODT
02

Targets

SERT (Sodium-dependent serotonin transporter)NET (Norepinephrine Transporter)MOR (Mu opioid receptor)

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