Drug intelligence / Profile preview

S-268024

Development stage
Unknown
Lead developer
Shionogi
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Intranasal
01

Overview

S-268024 is an intranasal COVID-19 vaccine candidate developed by Shionogi & Co., Ltd. Unlike traditional intramuscular vaccines, S-268024 is designed to be administered via the nasal passage to induce mucosal immunity (IgA) in the upper respiratory tract, which is the primary entry point for the SARS-CoV-2 virus, in addition to systemic immunity (IgG). It is a recombinant protein subunit vaccine that targets the spike protein of the virus. By stimulating local immunity in the nose and throat, it aims to not only prevent severe disease but also potentially reduce viral transmission more effectively than systemic vaccines.

Brand names
Nuvaxovid
Other names
Novavax COVID-19 Vaccine, AdjuvantedSARS-CoV-2 rSSARS-CoV2 rSSARS-CoV 2 rS
02

Targets

SARS-CoV-2 spike

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