S-3304 + paclitaxel + carboplatin

**S-3304 + paclitaxel + carboplatin** is an investigational three-drug combination regimen, where S-3304 is a matrix metalloproteinase inhibitor used alongside chemotherapy agents paclitaxel and carboplatin. Paclitaxel is a microtubule stabilizer that inhibits cell division by promoting tubulin polymerization and arresting mitosis, while carboplatin is a platinum-based DNA alkylating agent leading to apoptosis through DNA crosslinking. This combination is explored as a potential antineoplastic approach, targeting tumor invasion and metastasis by blocking matrix degradation (S-3304) and cytotoxicity to malignant cells (paclitaxel, carboplatin).

Other names

S-3304S3304S 3304paclitaxelcarboplatin