s-adenosyl-l-homoselenocysteine

S-Adenosyl-L-homoselenocysteine is an experimental small molecule and a selenium-containing analog of S-adenosyl-L-homocysteine (SAH). It belongs to the class of 5'-deoxyribonucleosides, specifically characterized by the replacement of the sulfur atom in the homocysteine moiety of SAH with a selenium atom. In biological systems, SAH is a potent competitive inhibitor of S-adenosyl-L-methionine (SAM)-dependent methyltransferases. Consequently, S-adenosyl-L-homoselenocysteine is primarily utilized as a biochemical research tool to investigate transmethylation pathways and the structural biology of methyltransferase enzymes. There is currently no evidence of clinical development, sponsoring pharmaceutical companies, or specific therapeutic indications for this compound.

Other names

S-Adenosyl-L-homoselenocysteineSe-Adenosyl-L-homocysteineSASeH