Drug intelligence / Profile preview

s-adenosyl-l-methionine disulfate p-toluene-sulfonate

Development stage
Unknown
Lead developer
Pharmavite
Modality
Small Molecules
Administration
Oral, Intravenous, Intramuscular
01

Overview

S-Adenosyl-L-methionine disulfate p-toluene-sulfonate is a stable salt form of S-Adenosyl-L-Methionine (SAMe), complexed with p-toluenesulfonic acid and bis(sulfates). SAMe is a naturally occurring compound involved in methyl group transfers and transsulfuration reactions in the body. As a supplement or drug, it has chemopreventive activity and is used for its potential benefits in treating depression, osteoarthritis, fibromyalgia, liver disorders including cholestatic liver diseases and alcoholic/non-alcoholic fatty liver disease. It may help restore glutathione concentrations in the liver and support detoxification processes. The precise mechanism of action involves acting as a methyl donor for various biochemical reactions essential for cellular function[1][2][6][9].

Brand names
ZentonilS-ametCodsyl
Other names
s‑adenosyl-l-methionine disulfate tosylateademetionine disulfate tosylateademetionine tosilate sulfateademetionine sulfate tosilateademetionine disulfate ditosylate(r)-s‑adenosyl-l-methionine disulfate tosylate(s)-s‑adenosyl-l-methionine disulfate tosylates‑adenosylmethionine disulfate tosylates‑adenosyl-l-methionine sulfate tosylates-(5′‑adenosyl)-l-methionine p-toluenesulfonic acid salt– adenosinemethylthioether, 5'-deoxy-, sulfate, 4-methylbenzenesulfonic acid salt
02

Targets

GSH (Glutathione synthesis / redox)

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