S-Caine

**S-Caine** is a topical local anesthetic formulation, primarily available as a eutectic mixture of **lidocaine 7% and tetracaine 7%** in cream or peel form, designed for rapid dermal anesthesia prior to minor medical, cosmetic, and dermatologic procedures. It functions by blocking voltage-gated **sodium channels** in nerve endings, preventing pain signal transmission; the eutectic formulation enhances skin penetration and onset speed compared to individual anesthetics. Developed for indications like venipuncture, non-ablative laser resurfacing, pulsed dye laser treatments, injections, tattooing, and minor surgeries, it provides effective numbing with a 20-30 minute application time, minimizing procedural discomfort while exhibiting a favorable safety profile for sensitive skin.[1][2][3][11]

Brand names

S-CaineS-Caine PatchS-Caine Peel

Other names

S-Cain Cream