Drug intelligence / Profile preview

S19 IPV

Development stage
Preclinical
Lead developer
Biological E
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

S19 IPV is an inactivated poliovirus vaccine (IPV) being developed by Bharat Biotech for the prevention of poliomyelitis. The vaccine is formulated using the S19 virus strain, which is a hyper-attenuated, genetically stabilized derivative of the Sabin strain. The S19 strain is designed to be highly restricted in its ability to replicate at human body temperature and has a significantly reduced risk of reverting to a neurovirulent form during manufacturing. This allows the vaccine to be produced under lower biosafety containment levels (such as BSL-2) compared to conventional IPVs that require high-containment facilities. S19 IPV is currently in preclinical development.

Other names
S19 inactivated poliovirus vaccineS-19 inactivated poliovirus vaccineS 19 inactivated poliovirus vaccineSabine S19 IPV
02

Targets

Poliovirus capsid proteins

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