Drug intelligence / Profile preview

S3273

Development stage
Unknown
Lead developer
Chengdu University of Traditional Chinese Medicine
01

Overview

S3273: sourced facts only. name: "A polycyclic aromatic naphthodianthrone compound, S3273, was the most potent CD39 enhancer with EC50 value of 5.66 μM." [PMID:41506549]; target: "A polycyclic aromatic naphthodianthrone compound, S3273, was the most potent CD39 enhancer with EC50 value of 5.66 μM." [PMID:41506549]; developer: "Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China; Key Laboratory of Acupuncture for Senile Disease (Chengdu University of TCM), Ministry of Education, Chengdu 611130, China; Acupunctcure Point Effects Key Laboratory of Sichuan Province, Chengdu 611130, China. Electronic address: [email protected]." [PMID:41506549]; stage: "S3273 calms cytokine storm to reverse lung damage in LPS-challenged mice, and these effects are at least partly through the modulation on CD39-P2X7R-IL-17A route." [PMID:41506549]

02

Targets

ENTPD1 (Ectonucleoside triphosphate diphosphohydrolase 1)

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