Drug intelligence / Profile preview

SA-41

Development stage
Unknown
Lead developer
National Institute of Pharmaceutical Education and Research Hyderabad
Modality
Small Molecules
01

Overview

SA-41: sourced facts only. name: "The in vitro CD73 inhibitory assay reveals that SA-41 and SA-26 exhibited potent activity with IC50 values of 2.83 ± 0.45 μM and 2.96 ± 0.46 μM, respectively." [PMID:42556589]; target: "The in vitro CD73 inhibitory assay reveals that SA-41 and SA-26 exhibited potent activity with IC50 values of 2.83 ± 0.45 μM and 2.96 ± 0.46 μM, respectively." [PMID:42556589]; developer: "Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER)-Hyderabad, Balanagar, Hyderabad 500037, Telangana, India." [PMID:42556589]; modality: "In this study, we report the design and synthesis of a novel series of salicylamido sulfonamide-based small-molecule CD73 inhibitors." [PMID:42556589]

02

Targets

NT5E (Cluster of Differentiation 73)

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